// Services · Clinic 45

Six ways to lose the weight for good.

Every service at Clinic 45 begins with Dr. Sleiman reviewing your labs and history in person. Treatment is adjusted at each visit — not auto-renewed. Six disciplines, one physician.

GLP-1 Receptor Agonist
Semaglutide injection — Clinic 45 Houston
No. 01

Semaglutide — the original GLP-1.

Semaglutide (branded Ozempic and Wegovy) works by mimicking the GLP-1 hormone — reducing appetite, slowing gastric emptying, and improving insulin sensitivity. At Clinic 45, the protocol is physician-titrated from week one, not administered at a fixed dose from a standing template.

  • Weekly subcutaneous injection, self-administered after training
  • Titration from 0.25 mg — adjusted monthly based on response and tolerance
  • Baseline labs required before initiation: HbA1c, thyroid, lipids, renal panel
  • Monthly in-office monitoring with Dr. Sleiman throughout the program
  • Side effect management built into every check-in — nausea protocols, dose holds
  • Combining with IV hydration and B12 recommended during adjustment phase
Frequency Weekly injection
Avg. timeline 12–24 weeks
Labs required Yes — before start
Book a semaglutide consult
GLP-1 + GIP Dual Agonist
Tirzepatide consultation at Clinic 45
No. 02

Tirzepatide — dual-action precision.

Tirzepatide (Zepbound and Mounjaro) targets two hormone receptors simultaneously — GLP-1 and GIP — making it the most effective FDA-approved weight loss medication currently available. In phase 3 clinical trials, patients lost up to 22.5% of their body weight. At Clinic 45, it is prescribed only after a full evaluation determines it is medically appropriate.

  • Weekly injection — from 2.5 mg, titrated up over 20–36 weeks
  • Superior efficacy data vs. semaglutide in head-to-head studies
  • Requires comprehensive labs: cardiovascular risk panel, thyroid, full metabolic
  • Not appropriate for patients with personal or family history of MTC or MEN 2
  • Quarterly monitoring — weight, labs, blood pressure, muscle mass assessment
  • Combination protocol available with hormone therapy for enhanced results
Frequency Weekly injection
Avg. timeline 20–36 weeks
Labs required Full panel required
Book a tirzepatide consult
Comprehensive Program
Medical weight loss consultation at Clinic 45 Houston
No. 03

Medical weight loss — the full picture.

For patients who want to understand the mechanics of their weight — not just receive a prescription. The comprehensive evaluation maps your metabolic baseline, identifies hidden barriers (thyroid, cortisol, insulin resistance), and produces a tailored roadmap that includes medication where appropriate and lifestyle guidance that is realistic for your actual life.

  • 60-minute initial evaluation with Dr. Sleiman — full history, exam, and labs
  • Body composition assessment to baseline muscle-to-fat ratio
  • Metabolic panel, thyroid, insulin, cortisol, full hormonal screen
  • Nutrition review with realistic caloric and macronutrient targets
  • Medication selection — GLP-1, phentermine, metformin, or combination
  • Monthly follow-up visits with documented progress tracking
Initial consult 60 minutes
Follow-ups Monthly
Labs included Comprehensive panel
Book a weight loss evaluation
Energy & Metabolism
B12 injection at Clinic 45 Houston
No. 04

B12 injections — energy restored.

Vitamin B12 deficiency is more common than most patients realise — particularly in those over 50, on metformin, or eating a restricted diet during weight loss. Clinic 45 uses methylcobalamin, the most bioavailable B12 form, administered intramuscularly for immediate systemic absorption. The result is improved energy, sharper cognition, and support for the metabolic processes that drive fat burning.

  • Methylcobalamin intramuscular injection — administered in clinic
  • Available weekly or biweekly depending on deficiency and goals
  • Strongly recommended during GLP-1 programs to offset appetite-reduction fatigue
  • Can be paired with IV hydration in the same visit
  • No prescription required for standalone B12 — walk-in available
Form Methylcobalamin IM
Frequency Weekly or biweekly
Session length Under 10 minutes
Book a B12 injection
Clinical IV Infusion
IV Hydration therapy at Clinic 45 Houston
No. 05

IV Hydration — clinical-grade restoration.

IV therapy at Clinic 45 is not the mobile wellness lounge model. It is administered in a supervised clinical setting, with formulations that Dr. Sleiman selects based on patient presentation and goals. From basic electrolyte repletion to NAD+ infusions for energy and cellular recovery, every drip is prepared and monitored by a licensed clinical team.

  • Standard hydration: 1L saline + electrolyte repletion (30–45 min)
  • Myers' Cocktail: magnesium, B vitamins, vitamin C — immune and energy support
  • Recovery blend: amino acids, glutathione, electrolytes — post-exertion or illness
  • NAD+ infusion: 250–500 mg for cellular energy, cognitive clarity, metabolism
  • Weight loss support blend: B12, B-complex, amino acids, lipotropics
  • Add-on boosters: zinc, toradol, Zofran (nausea) — physician-authorised only
Session time 30–90 minutes
Setting Supervised clinic
Formulations 5 blends + add-ons
Book an IV session
Labs-Driven HRT & TRT
Hormone therapy consultation at Clinic 45 Houston
No. 06

Hormone Therapy — balance, restored.

Hormonal imbalance is one of the most underdiagnosed obstacles to sustainable weight loss. Low testosterone in men, oestrogen/progesterone dysregulation in women, and subclinical thyroid dysfunction all drive fat accumulation and make GLP-1 medications less effective. Dr. Sleiman runs a comprehensive hormonal panel before any recommendation is made — and adjustments are based on quarterly labs, never on symptoms alone.

  • Men: testosterone replacement therapy (TRT) — injection, pellet, or topical
  • Women: oestrogen, progesterone, and testosterone HRT — bioidentical options
  • Thyroid: evaluation and management of hypothyroidism and subclinical dysfunction
  • DHEA, cortisol, growth hormone assessment included in comprehensive panel
  • Quarterly monitoring labs — no standing orders without review
  • Frequently combined with GLP-1 program for compounding fat loss results
Eval required Full labs + exam
Monitoring Quarterly labs
Delivery Injection, pellet, topical
Book a hormone evaluation

Not sure which service is right for you?

The first consultation answers that question. Dr. Sleiman reviews your labs, your history, and your goals — then recommends the protocol that actually fits your biology. No packages pushed, no upselling.

Book your free consult Call 713 · 999 · 5161